Organometallic Compounds
Medchemexpress LLC Bis-PEG3-NHS ester | 1314378-16-9 | 97.0% | 444.39 g/mol | C18H24N2O11 | 500 MG
Bis-PEG3-NHS ester is a non-cleavable PEG-based bifunctional linker containing two N-hydroxysuccinimide (NHS) ester reactive groups used for bioconjugation and antibody-drug conjugate (ADC) construction. The three-unit PEG spacer increases hydrophilicity and solubility, while the NHS esters enable efficient coupling to primary amines on proteins and peptides.
- Non-cleavable 3-unit PEG linker for stable conjugation.
- Contains two NHS ester groups for bioconjugation to primary amines.
- Improves solubility and hydrophilicity of conjugates.
- Available in multiple package sizes, including 500 mg.
- Provided with SDS, COA, and product data sheet for quality and safety information.
Medchemexpress LLC N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid | 2183440-74-4 | 98.1% | C29H55N5O13 | 100 MG
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It also functions as a click chemistry reagent, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- PEG-based PROTAC linker for PROTAC synthesis
- Functions as a click chemistry reagent
- Azide group facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- PROTACs leverage the ubiquitin-proteasome system for selective protein degradation
Medchemexpress LLC M-PEG3-azide | 74654-06-1 | 98.0% | C7H15N3O3 | 500 MG
m-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Participates in CuAAc reactions with Alkyne groups
- Participates in SPAAC reactions with DBCO or BCN groups
Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 250 MG
NH-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group, and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based protac linker
- Used in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
Medchemexpress LLC 2-amino-4-(ethylthio)butanoic acid | 67-21-0 | MFCD00063102 | 99.4% | 163.24 g·mol⁻¹ | C6H13NO2S | 10 G
2-Amino-4-(ethylthio)butanoic acid is a methionine-derived amino acid analogue supplied as a research-grade biochemical reagent. It is intended for laboratory studies of amino acid metabolism, enzyme assays, and nutritional or pharmacological investigations; not for human or clinical use.
- High purity (99.36%).
- Molecular weight 163.24 g·mol⁻¹.
- Soluble in water for aqueous assays.
- Available in multiple pack sizes for laboratory experiments.
- Provided with certificate of analysis and safety data sheet.
Medchemexpress LLC Tri(Amino-PEG3-amide)-amine | 2523025-40-1 | 98.0% | C33H69N7O12 | 50 MG
Tri(Amino-PEG3-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- For research use only.